OverView of Protein Structure Prediction in Bioinformatics
نویسنده
چکیده
rotein structure prediction from a sequence is one of the high focus problems for researchers.This is a very useful application of bioinformatics as the experimental techniques like X-ray crystallography are time consuming.The fundamental issue is how can we predict the 3-D shape of a protein from its amino acid sequence. In this paper we will learn how to predict protein structure and function based on the amino acid sequence. Keywords— Bioinformatics,Protein,Primary,Secondary,Tertiary,Quaternary.
منابع مشابه
Protein Secondary Structure Prediction: a Literature Review with Focus on Machine Learning Approaches
DNA sequence, containing all genetic traits is not a functional entity. Instead, it transfers to protein sequences by transcription and translation processes. This protein sequence takes on a 3D structure later, which is a functional unit and can manage biological interactions using the information encoded in DNA. Every life process one can figure is undertaken by proteins with specific functio...
متن کاملB and T-Cell Epitope Prediction of the OMP25 Antigen for Developing Brucella melitensis Vaccines for Sheep
Brucellosis, produced by Brucella species, is a disease that causes severe economic losses for livestock farms worldwide Due to serious economic and medical consequences of this disease, many efforts have been made to prevent the infection through the use of recombinant vaccines based on Brucella outer membrane protein (OMP) antigens. In the present study, a wide range of on-line prediction sof...
متن کاملBioinformatics prediction and experimental validation of VH antibody fragment interacting with Neisseria meningitidis factor H binding protein
Objective(s): We previously conducted an in silico research on the interactions between the ribosome display-selected single chain variable fragment (scFv) and factor H binding protein (fHbp) of Neisseria meningitidis. We found that heavy chain variable (VH) fragment of this scFv had considerable affinity to fHbp. These results led us to evaluate the ability of this sm...
متن کاملBioinformatics Analysis of Upstream Region and Protein Structure of Fungal Phytase Gene
Phytase increases the bioavailability of phytate phosphorus in seed-based animal feeds and reduces the phosphorus pollution of animal waste. Since most animal feeds for pellets are heated up to 65-80 °C, the production of a thermostable structure for phytase can be useful. In this study, we sought to perform bioinformatics analysis of the upstream region and protein structure of fungal phytase ...
متن کاملComputational Intelligence
In this chapter, we present a brief overview of bioinformatics and computational intelligence (CI) methods including artificial neural networks, genetic algorithms, and fuzzy systems. A number of representative applications of CI methods in bioinformatics are discussed, including CI methods for gene expression analysis, for multiple sequence alignment, for protein-protein interaction prediction...
متن کاملIn silico investigation of lactoferrin protein characterizations for the prediction of anti-microbial properties
Lactoferrin (Lf) is an iron-binding multi-functional glycoprotein which has numerous physiological functions such as iron transportation, anti-microbial activity and immune response. In this study, different in silico approaches were exploited to investigate Lf protein properties in a number of mammalian species. Results showed that the iron-binding site, DNA and RNA-binding sites, signal pepti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2014